Cancer Terms

F344 Rat Strain

Cancer Terms -> Organisms -> Animal -> Vertebrate -> Mammal -> Rodent -> Muridae -> Rat -> Common Rattus Norvegicus Strains -> F344 Rat Strain

F344 Rat Strain Definition

Most animals older than 2 years exhibit small local areas of nephritis; less than 25% show severe nephritis (Snell 1967). Tumors: Mammary tumors 41% in females and 23% in males, pituitary adenomas 36% in females and 24% in males, testicular interstitial cell tumors 85% in males. Other tumor types less common (Sass et al 1975). Thyroid carcinoma 22% (Lindsey et al 1968). Interstitial cell testicular tumors 65%, mononuclear cell leukemia 24%, subcutaneous fibroadenoma 9% in females. Both sexes have a 5% incidence of nodular hyperplasia of the liver.

F344 Rat Strain Synonyms

F344, Rat Strain, F344, Fisher 344

Terms in F344 Rat Strain category



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