FAK Family Tyrosine Kinase

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Enzyme -> Transferase -> Phosphotransferase -> Kinase -> Protein Kinase -> Protein Tyrosine Kinase -> FAK Family Tyrosine Kinase

FAK Family Tyrosine Kinase Definition

Soluble cytoplasmic non-receptor FAK (Focal Adhesion Kinase) Family Tyrosine Kinases catalyze the phosphorylation of tyrosine residues in proteins with ATP or other nucleotides as phosphate donors. FAK is found in intracellular signaling focal adhesion complexes following engagement of the extracellular matrix by integrins. The C-terminal 'focal adhesion targeting' (FAT) region is necessary and sufficient for localizing FAK to focal adhesions.

FAK Family Tyrosine Kinase Synonyms

Terms in FAK Family Tyrosine Kinase category

Focal Adhesion Kinase-1
PTK2B Protein Tyrosine Kinase-2 Beta