Cancer Terms

FGF3 wt Allele

Cancer Terms -> Gene -> Growth Factor Gene -> Fibroblast Growth Factor Gene Family -> FGF3 Gene -> FGF3 wt Allele

FGF3 wt Allele Definition

Human FGF3 wild-type allele is located within 11q13 and is approximately 9 kb in length. This allele, which encodes INT-2 proto-oncogene protein, plays a role in cellular growth and signal transduction. Frequent amplification of this allele has been found in human tumors, which may be important for neoplastic transformation and tumor progression.

FGF3 wt Allele Synonyms

FGF3 wt Allele, Fibroblast Growth Factor 3 (Murine Mammary Tumor Virus Integration Site (v-int-2) Oncogene Homolog) wt Allele, Fibroblast Growth Factor 3 Gene, INT-2, INT2, MMTV Integration Site Gene 2

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