FGFR1 wt Allele

Cancer Terms -> Gene -> Ligand Binding Protein Gene -> Receptor Gene -> Growth Factor Receptor Gene -> Fibroblast Growth Factor Receptor Family Gene -> FGFR1 Gene -> FGFR1 wt Allele

FGFR1 wt Allele Definition

Human FGFR1 wild-type allele is located within 8p11.2-p11.1 and is approximately 56 kb in length. This allele, which encodes basic fibroblast growth factor receptor 1 protein, is involved in the mediation of binding between both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene are associated with several diseases, including Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2. Further, chromosomal aberrations involving the gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome.

FGFR1 wt Allele Synonyms

FGFR1 wt Allele, FGFBR, FGFR1, FLG Gene, FLT2 Gene, FMS-Like Gene, FMS-Like Tyrosine Kinase 2 Gene, Fibroblast Growth Factor Receptor 1 (FMS-Related Tyrosine Kinase 2, Pfeiffer Syndrome) wt Allele, Fibroblast Growth Factor Receptor 1 Gene

FGFR1 wt Allele

FGFR1 wt Allele Definition

FGFR1 wt Allele Synonyms

Terms in FGFR1 wt Allele category