FGFR3 wt Allele

Cancer Terms -> Gene -> Ligand Binding Protein Gene -> Receptor Gene -> Growth Factor Receptor Gene -> Fibroblast Growth Factor Receptor Family Gene -> FGFR3 Gene -> FGFR3 wt Allele

FGFR3 wt Allele Definition

Human FGFR3 wild-type allele is located in the vicinity of 4p16.3 and is approximately 15 kb in length. This allele, which encodes fibroblast growth factor receptor 3 protein, is involved in mitogenesis, differentiation, and bone development and maintenance. Alterations in the gene resulting in defects cause, achondroplasia, crouzon syndrome, thanatophoric dysplasia, coronal synostosis, hypochondroplasia, bladder and cervix cancers.

FGFR3 wt Allele Synonyms

FGFR3 wt Allele, ACH, CEK2, FGFR3, Fibroblast Growth Factor Receptor 3 (Achondroplasia, Thanatophoric Dwarfism) wt Allele, HSFGFR3EX, JTK4

Terms in FGFR3 wt Allele category

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