FLI1 Transcription Factor
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ETS Family Protein -> FLI1 Transcription Factor
FLI1 Transcription Factor Definition
Similar to other ETS transcription factors, ERGB Transcription Factor (FLI1) regulates expression of the TGF-beta type II receptor gene. FLI1 contains one PNT domain, can form homodimers or heterodimers with ETV6/TEL1, and recognizes the sequence C[CA]GGAAGT. Two isoforms may be produced by alternative splicing. A form of Ewing's sarcoma is characterized by the chromosomal translocation t(11;22)(q24;q12), which involves FLI1 and EWS. (NCI)
FLI1 Transcription Factor Synonyms
FLI1 Transcription Factor, ERGB Transcription Factor, FLI1, FLI1 Protein, Friend Leukemia Virus Integration 1 Protein, Friend Leukemia Virus Integration 1 Transcription Factor
Terms in FLI1 Transcription Factor category
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