Cancer Terms

FLI1 Transcription Factor

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Regulatory Protein -> Transcription Regulatory Protein -> Transcription Factor -> ETS Family Protein -> FLI1 Transcription Factor

FLI1 Transcription Factor Definition

Similar to other ETS transcription factors, ERGB Transcription Factor (FLI1) regulates expression of the TGF-beta type II receptor gene. FLI1 contains one PNT domain, can form homodimers or heterodimers with ETV6/TEL1, and recognizes the sequence C[CA]GGAAGT. Two isoforms may be produced by alternative splicing. A form of Ewing's sarcoma is characterized by the chromosomal translocation t(11;22)(q24;q12), which involves FLI1 and EWS. (NCI)

FLI1 Transcription Factor Synonyms

FLI1 Transcription Factor, ERGB Transcription Factor, FLI1, FLI1 Protein, Friend Leukemia Virus Integration 1 Protein, Friend Leukemia Virus Integration 1 Transcription Factor

Terms in FLI1 Transcription Factor category



Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods

No reproduction or republication permitted.