Cancer Terms

FOS Protein

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Ligand Binding Protein -> DNA Binding Protein -> FOS Family Protein -> FOS Protein

FOS Protein Definition

FOS is involved in growth-related transcriptional control, is a key regulator of osteoclast-macrophage lineage determination, and is a major component of the heterodimeric DNA-binding AP-1 transcription factor complex, which includes JUN family members. Both proteins contain a bZIP region. AP-1 binds to TREs (TPA-responsive elements) in the promoters of target genes. (from OMIM 164810 and NCI)

FOS Protein Synonyms

FOS Protein, FBJ Murine Osteosarcoma Viral Oncogene Homolog, FOS, c-fos Protein

Terms in FOS Protein category



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