FPS-FES Protein
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Gene Product ->
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Transferase ->
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Protein Tyrosine Kinase ->
Tyrosine-Protein Kinase FES-FPS -> FPS-FES Protein
FPS-FES Protein Definition
Human FPS-FES Protein is a product of a mutated variant (Oncogene FPS-FES) of FES Gene (FES/FPS Subfamily), which encodes 822 aa 93-kDa Tyrosine-Protein Kinase FES/FPS, a tyrosine-specific protein kinase involved in normal hematopoiesis and containing an FCH and SH2 domain. The FES chromosomal location is linked to a translocation identified in patients with acute promyelocytic leukemia. A truncated transcript is generated utilizing a start site in a far downstream exon. FPS-FES Protein disrupts normal cell function.
FPS-FES Protein Synonyms
FPS-FES Oncoprotein
Terms in FPS-FES Protein category
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