Cancer Terms

Fas-Activated Serine-Threonine Kinase

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Enzyme -> Transferase -> Phosphotransferase -> Kinase -> Protein Kinase -> Serine-Threonine Protein Kinase -> Fas-Activated Serine-Threonine Kinase

Fas-Activated Serine-Threonine Kinase Definition

Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas by human FASTK Gene (Ser/Thr PK Family), 3 alternative isoforms of 549-aa 61-kD Fas-Activated Serine/Threonine Kinase are rapidly activated during Fas-mediated apoptosis as serine/threonine dephosphorylated FASTK, which phosphorylates TIA1, a key apoptosis-promoting nuclear RNA-binding protein. (NCI)

Fas-Activated Serine-Threonine Kinase Synonyms

Fas-Activated Serine/Threonine Kinase, FAST Kinase, FASTK

Terms in Fas-Activated Serine-Threonine Kinase category



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