Fatty Acid Synthase
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Fatty Acid Synthase Definition
Fatty acid synthase (FAS) is a key metabolic enzyme catalyzing the synthesis of long-chain saturated fatty acids. It plays a central role in the production of surfactant in fetal lungs, in the supply of fatty components of milk, and in the conversion and storage of energy in liver and adipose tissue. Remarkably high levels of FAS expression are found in the majority of human epithelial cancers. Experimental manipulation suggests a link between FAS overexpression and dysregulation of membrane composition and functioning in tumor cells. (from Biochem Biophys Res Commun 2003;302:898-903)
Fatty Acid Synthase Synonyms
Fatty Acid Synthase, EC 2.3.1.85, FAS, FASN
Terms in Fatty Acid Synthase category
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