Cancer Terms

Fenoldopam Mesylate

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Agent Affecting Nervous System -> Dopamine Agonist -> Fenoldopam Mesylate

Fenoldopam Mesylate Definition

The mesylate salt form of fenoldopam, a benzazepine derivative with rapid-acting vasodilator activity. Fenoldopam mesylate is a racemic mixture of S- and R- isomers; the latter is responsible for the biological activity and has a significantly higher affinity for dopamine D1-like receptors (D1 and D5) as well as moderate affinity to alpha-2 adrenergic receptors. This agent selectively activates the dopamine D1-like receptor, thereby causing vasodilatation and increasing renal perfusion.

Fenoldopam Mesylate Synonyms

Fenoldopam Mesylate, 6-Chloro-2,3,4,5-tetrahydro-1-(p-hydroxyphenyl)-1H-3-benzazepine-7,8-diol methanesulfonate(salt), Corlopam, FENOLDOPAM MESYLATE, Fenoldopam mesylate

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