Cancer Terms

Fenretinide

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Antineoplastic Agent -> Cell Differentiating Agent -> Differentiation Inducer -> Retinoic Acid Agent -> Fenretinide

Fenretinide Definition

An orally-active synthetic phenylretinamide analogue of retinol (vitamin A) with potential antineoplastic and chemopreventive activities. Fenretinide binds to and activates retinoic acid receptors (RARs), thereby inducing cell differentiation and apoptosis in some tumor cell types. This agent also inhibits tumor growth by modulating angiogenesis-associated growth factors and their receptors and exhibits retinoid receptor-independent apoptotic properties. (NCI04)

Fenretinide Synonyms

Fenretinide, 4-(all-trans-retino-yl)aminophenol, 4-HPR, 4-Hydroxyphenylretinamide, All-trans-4'-Hydroxyretinanilide, FENRETINIDE, Fenretinimide, HPR-4, McN-R-1967, N-(4-hydroxyphenyl)retinamide, all-trans-4'-hydroxyretinanilide, all-trans-N-(4-Hydroxyphenyl)retinamide, all-trans-N-4'-hydroxyretinanilide, fenretinide

Terms in Fenretinide category



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