Fibroblast Growth Factor-1

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Growth Factor -> Heparin Binding Growth Factor -> Fibroblast Growth Factor -> Fibroblast Growth Factor-1

Fibroblast Growth Factor-1 Definition

A modifier of endothelial cell migration and proliferation, Fibroblast Growth Factor 1 may be important in neovascularization. Acidic Fibroblast Growth Factor and alpha-ECGF are derived from FGF1 by posttranslational processing. FGF1 causes the foregut endoderm to develop into the liver. The hepatogenic response is restricted to endoderm tissue, which selectively co-expresses FGF receptors 1 and 4. Different FGF signals appear to initiate distinct phases of liver development during mammalian organogenesis. FGF1 binding to FGFR2 is accompanied by binding of a heparin decasaccharide. (from OMIM 131220 and NCI)

Fibroblast Growth Factor-1 Synonyms

Fibroblast Growth Factor 1, Acidic Fibroblast Growth Factor, Alpha Fibroblast Growth Factor, Beta-Endothelial Cell Growth Factor, Endothelial Cell Growth Factor, Alpha, Endothelial Cell Growth Factor, Beta, FGF-1, FGF1, Heparin Binding Growth Factor 1, Heparin Binding Growth Factor-1, Prostatropin, aFGF

Terms in Fibroblast Growth Factor-1 category

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