Formestane
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Steroidal Aromatase Inhibitor -> Formestane
Formestane Definition
A synthetic steroidal substance with antineoplastic activity. Formestane binds irreversibly to and inhibits the enzyme aromatase, thereby blocking the conversion of cholesterol to pregnenolone and the peripheral aromatization of androgenic precursors into estrogens. (NCI04)
Formestane Synonyms
Formestane, 4-Hydroxyandrost-4-ene-3,17-dione, 4-Hydroxyandrostenedione, 4-OHA, 4-OHAD, CGP-32349, Lentaron
Terms in Formestane category
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