Frizzled-7 Protein
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Frizzled-7 Protein Definition
Frizzled 7, encoded by the human FZD7 gene, is a G protein-coupled receptor for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression downregulates APC function and enhances beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. (From LocusLink and NCI)
Frizzled-7 Protein Synonyms
Frizzled 7, FZD7, FZD7 Protein, FZE3, Frizzled Homolog 7 (Drosophila), Frizzled, Drosophila, Homolog of, 7, Frizzled-7, Fz-7, hFz7
Terms in Frizzled-7 Protein category
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