Cancer Terms

Furin Preproprotein

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Enzyme -> Hydrolase -> Protease -> Serine Protease -> Furin Preproprotein

Furin Preproprotein Definition

Paired basic amino acid cleaving enzyme is an ubiquitous proprotein endoprotease that functions within secretory pathways and is localized in the trans Golgi network. PACE cleaves protein substrates at RX(K/R)R consensus motifs and plays a significant role in tumor progression. (from OMIM 136950 and NCI)

Furin Preproprotein Synonyms

Furin Preproprotein, FURIN, PACE Protein, Paired Basic Amino Acid Cleaving Enzyme

Terms in Furin Preproprotein category



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