G Protein-Coupled Receptor

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Ligand Binding Protein -> Receptor -> Cell Surface Receptor -> G Protein-Coupled Receptor

G Protein-Coupled Receptor Definition

Cell surface receptors that are coupled to G-proteins (GTP-binding protein). G-protein coupled receptors are thought to have seven membrane spanning domains and have been divided into 2 subclasses: those in which the binding site is in the extracellular domain for example receptors for glycoprotein hormones, such as thyroid stimulating hormone (TSH) and follicle-stimulating hormone (FSH) and those in which the ligand binding site is likely to be in the plane of the 7 transmembrane domains for example rhodopsin and receptors for small neurotransmitters and hormones for example muscarinic acetylcholine receptor.

G Protein-Coupled Receptor Synonyms

G Protein-Coupled Receptor, G Protein-Complex Receptor, G Protein-Complex Receptors, G-Protein Coupled Receptor, GPCR

Terms in G Protein-Coupled Receptor category

Alpha Adrenergic Receptor
Angiotensin Receptor-2
Beta Adrenergic Receptor
Bombesin-Like Receptor-3
Bradykinin Receptor-B2
CD97 Antigen
Chemokine-Like Receptor-1
Chemokine Receptor-HM74
Cholecystokinin-B Receptor
Coagulation Factor-II Receptor
Corticotropin-Releasing Factor Receptor 1
Dopamine Receptor
Formyl Peptide Receptor-1
Frizzled-2 Protein
Frizzled-3 Protein
Frizzled-4 Protein
Frizzled-6 Protein
Frizzled-7 Protein
Frizzled-9 Protein
G Protein-Coupled Receptor-17
G Protein-Coupled Receptor-2
G Protein-Coupled Receptor-32
G Protein-Coupled Receptor-39-1
G Protein-Coupled Receptor-54-1
G Protein-Coupled Receptor-68
Galanin Receptor-2
Gastric Inhibitory Polypeptide Receptor
Gonadotropin-Releasing Hormone Receptor
Histamine Receptor-H2
Leukotriene-B4 Receptor
MAS1 Protein
Melatonin Receptor
Melatonin Receptor Type 1B
Metabotropic Glutamate Receptor-1
Metabotropic Glutamate Receptor-5
Metabotropic Glutamate Receptor-6
Muscarinic Acetylcholine Receptor-M1
Muscarinic Acetylcholine Receptor-M3
Muscarinic Acetylcholine Receptor-M4
Muscarinic Acetylcholine Receptor-M5
Neuromedin-B Receptor
Olfactory Receptor-1G1
Orphan G-Protein Coupled Receptor
Protocadherin Flamingo-2 Protein
Purinergic Receptor
Retinoic Acid Induced-3 Protein
Secretin Receptor
Serotonin 2A Receptor
Smoothened Homolog Protein
Tachykinin Receptor-1
Tachykinin Receptor-3
Thyroid Stimulating Hormone Receptor
Vasoactive Intestinal Peptide Receptor-1
Vasopressin Receptor