Cancer Terms

G Protein-Coupled Receptor Kinase-6

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Enzyme -> Transferase -> Phosphotransferase -> Kinase -> Protein Kinase -> Serine-Threonine Protein Kinase -> G Protein-Coupled Receptor Kinase Family -> G Protein-Coupled Receptor Kinase-6

G Protein-Coupled Receptor Kinase-6 Definition

Widely expressed by human GPRK6 Gene (GPRK Family), alternative isoforms A (576-aa) and B (589-aa) of membrane-bound 66-kDa G Protein-Coupled Receptor Kinase 6, containing an RGS domain and DLG and ENIL motifs, specifically Ser/Thr phosphorylate activated forms of GPCRs and may be involved in desensitization of D2/D3 dopamine receptors. (NCI)

G Protein-Coupled Receptor Kinase-6 Synonyms

G Protein-Coupled Receptor Kinase 6, EC 2.7.1.-, G Protein-Coupled Receptor Kinase GRK6, GPRK6

Terms in G Protein-Coupled Receptor Kinase-6 category



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