Cancer Terms

G Protein-Coupled Receptor Kinase-7

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Enzyme -> Transferase -> Phosphotransferase -> Kinase -> Protein Kinase -> Serine-Threonine Protein Kinase -> G Protein-Coupled Receptor Kinase Family -> G Protein-Coupled Receptor Kinase-7

G Protein-Coupled Receptor Kinase-7 Definition

Expressed in retina by human GPRK7 Gene (GPRK family), membrane-bound 553-aa 62-kDa G Protein-Coupled Receptor Kinase 7 is a Ser/Thr kinase containing an RGS domain, a C-terminal CaaX motif for isoprenylation and carboxymethylation, an autophosphorylation site (Ser491), and a geranylgeranylation motif. GRK7 catalyzes rhodopsin phosphorylation, initiating their deactivation in a light-dependent manner. (NCI)

G Protein-Coupled Receptor Kinase-7 Synonyms

G Protein-Coupled Receptor Kinase 7, EC 2.7.1.-, G Protein-Coupled Receptor Kinase GRK7, GPRK7

Terms in G Protein-Coupled Receptor Kinase-7 category



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