GCLC wt Allele

Cancer Terms -> Gene -> Protein Complex Subunit Gene -> GCLC Gene -> GCLC wt Allele

GCLC wt Allele Definition

Human GCLC wild-type allele is located within 6p12 and is approximately 48 kb in length. This allele, which encodes glutamate--cysteine ligase catalytic subunit protein, is involved in the biosynthesis of glutathione. Heritable defects in the GCLC gene are associated with hemolytic anemia (due to deficiency of gamma-glutamylcysteine synthetase) and susceptibility to myocardial infarction.

GCLC wt Allele Synonyms

GCLC wt Allele, GCS, GLCL, GLCLC, Glutamate-Cysteine Ligase, Catalytic Subunit wt Allele

Terms in GCLC wt Allele category

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