GDNF wt Allele

Cancer Terms -> Gene -> Growth Factor Gene -> GDNF Gene -> GDNF wt Allele

GDNF wt Allele Definition

: Human GDNF wild-type allele is located within 5p13.1-p12 and is approximately 24 kb in length. This allele, which encodes glial cell line-derived neurotrophic factor protein, is involved in both the survival and differentiation of dopaminergic neurons and in apoptotic motor neuron protection induced by axotomy. Mutantions in the gene produce variant alleles that are associated with Hirschsprung disease.

GDNF wt Allele Synonyms

GDNF wt Allele, Glial Cell Derived Neurotrophic Factor wt Allele

Terms in GDNF wt Allele category

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