GFAP wt Allele
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GFAP wt Allele Definition
Human GFAP wild-type allele is located in the vicinity of 17q21and is approximately 10 kb in length. This allele, which encodes glial fibrillary acidic protein, may play a role in the modulation of both motility and cellular morphology of astrocytes. Mutations in the gene are associated with Alexander disease, which is characterized by both progressive leukoencephalopathy and loss of neuronal myelination with age.
GFAP wt Allele Synonyms
GFAP wt Allele, FLJ45472, Glial Fibrillary Acidic Protein wt Allele
Terms in GFAP wt Allele category
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