GLI Protein
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GLI Protein Definition
The GLI1 Protein, a Kruppel family protein, is homologous to Drosophila Cubitus interruptus and contains five DNA-binding zinc finger repeats, implicated in transduction of the SHH signal; an endodermal signal that controls hindgut patterning and lung growth. The GLI1 gene is found amplified in a malignant glioma. (from OMIM 165220 and NCI)
GLI Protein Synonyms
GLI Protein, GLI, GLI1, GLI1 Protein, Glioma Associated Oncogene Homolog 1 Protein
Terms in GLI Protein category
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