Cancer Terms

GPI-Transamidase Component-PIGU

Cancer Terms -> Gene Product -> Protein -> Protein Complex Subunit -> GPI-Transamidase Component-PIGU

GPI-Transamidase Component-PIGU Definition

Ubiquitously expressed by human CDC91L1 Gene (PIGU Family), conserved 435-aa 50-kD GPI Transamidase Component PIGU is an integral ER membrane protein containing 9 putative transmembrane domains, with similarity to Cdc91 (S. cerevisiae), and a critical subunit of the GPI transamidase complex (PIGU, PIGK/GPI8, PIGS, PIGT, and GPAA1/GAA1) that attaches posttranslational GPI-anchors to the C-termini of cell surface proteins attached to membranes via GPI. PIGU may be involved in recognition of the GPI attachment signal or the lipid portion of GPI. (NCI)

GPI-Transamidase Component-PIGU Synonyms

GPI Transamidase Component PIGU, CDC91-Like 1 Protein, CDC91L1, Cell Division Cycle 91-Like 1 Protein, Cell Division Cycle Protein 91-Like 1 Protein, GPI Transamidase Component, PIGU, Phosphatidylinositol-Glycan Biosynthesis Class U Protein, UNQ3055/PRO9875

Terms in GPI-Transamidase Component-PIGU category



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