Cancer Terms

GSK-Binding Domain

Cancer Terms -> Anatomic Structure System or Substance -> Microanatomy -> Macromolecular Structure -> Protein Structure -> Protein Domain -> Ligand Binding Domain -> Protein Binding Domain -> GSK-Binding Domain

GSK-Binding Domain Definition

The GSK-Binding Domain of AXIN2 mediates interaction with GSK3-Beta. Involved in regulation of the WNT signaling pathway, AXIN2 organizes an APC/Beta-Catenin/GSK3-Beta/ AXIN2 complex that leads to Beta-Catenin degradation. (NCI)

GSK-Binding Domain Synonyms

GSK-Binding Domain

Terms in GSK-Binding Domain category



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