Gamma-Glutamylcysteine Synthetase Catalytic Subunit
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Gamma-Glutamylcysteine Synthetase Catalytic Subunit Definition
Encoded by human GCLC Gene (Glutamate-Cysteine Ligase 3 Family), 636-aa 73-kDa Gamma-Glutamylcysteine Synthetase Catalytic Subunit is the heavy subunit of heterodimeric Gamma-Glutamylcysteine Synthetase, first rate limiting enzyme of the glutathione biosynthesis pathway. GCLC defects cause hemolytic anemia. (NCI)
Gamma-Glutamylcysteine Synthetase Catalytic Subunit Synonyms
Gamma-Glutamylcysteine Synthetase Catalytic Subunit, GCLC, GCS, GCS Heavy Chain, GLCL, GLCLC, Gamma-ECS, Gamma-Glutamylcysteine Synthetase, Glutamate-Cysteine Ligase Catalytic Subunit
Terms in Gamma-Glutamylcysteine Synthetase Catalytic Subunit category
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