Gastrin Releasing Peptide
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Gastrin Releasing Peptide Definition
Gastrin-releasing peptide (GRP) is the equivalent in mammals of the amphibian bombesin. Infusion of either GRP or bombesin increases plasma levels of gastrin, pancreatic polypeptide, glucagon, gastric inhibitory peptide, and insulin. It is widely distributed in the gastrointestinal tract and in the nervous system. In normal adult mammal GRP is strictly a neuropeptides and functions in a neurotransmitter-like fashion. In the fetus, a larger form of GRP acts as a hormone and exerts growth factor-like activity on many organs, aiding in development.
Gastrin Releasing Peptide Synonyms
Gastrin Releasing Peptide, GRP, Mammalian Bombesin
Terms in Gastrin Releasing Peptide category
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