Cancer Terms

General Transcription Factor-IIH1-62kDa

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Regulatory Protein -> Transcription Regulatory Protein -> Transcription Factor -> Basal Transcription Factor -> General Transcription Factor-IIH1-62kDa

General Transcription Factor-IIH1-62kDa Definition

Expressed in testis by human GTF2H1 Gene, General Transcription Factor IIH1 62kDa is a subunit of TFIIH, a multisubunit factor of at least 10 proteins involved in transcription, nucleotide excision repair, and cell cycle regulation. p62 is one of six subunits that constitutes the TFIIH core; the holoenzyme contains the ternary kinase CAK complex. Lacking any known motifs or enzymatic activity p62 may have only an architectural role. (NCI)

General Transcription Factor-IIH1-62kDa Synonyms

General Transcription Factor IIH1 62kDa, BTF2-p62, Basic Transcription Factor 62kDa Subunit, GTF2H1, General Transcription Factor IIH1, TFIIH Basal Transcription Factor Complex p62 Subunit

Terms in General Transcription Factor-IIH1-62kDa category



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