General Transcription Factor-IIIC2 Beta Subunit

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Regulatory Protein -> Transcription Regulatory Protein -> Transcription Factor -> Basal Transcription Factor -> General Transcription Factor-IIIC2 Beta Subunit

General Transcription Factor-IIIC2 Beta Subunit Definition

Encoded by human GTF3C2 Gene, 110-kD ubiquitous General Transcription Factor IIIC2 Beta Subunit is the beta subunit of general transcription factor GTF3C, a component of RNA polymerase III and essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA. To initiate RNA synthesis, RNA polymerases need GTFs to assemble in a promoter-bound complex and recruit RNA polymerase. GTF3C2 contains stretches of acidic and basic regions, potential acidic and basic helices, and 5 putative WD40 repeats. (NCI)

General Transcription Factor-IIIC2 Beta Subunit Synonyms

General Transcription Factor IIIC2 Beta Subunit, GTF3C2, General Transcription Factor IIIC2 Beta 110kDa, TFIIIC-Beta, TFIIIC110

Terms in General Transcription Factor-IIIC2 Beta Subunit category

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