Glutamic-Pyruvate Transaminase
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SGPT-ALT Protein -> Glutamic-Pyruvate Transaminase
Glutamic-Pyruvate Transaminase Definition
Expressed in liver, kidney, heart, fat, and skeletal muscle by glucocorticoid-induced human GPT Gene (Alanine Aminotransferase Family), 495-aa 54-kDa Glutamic-Pyruvate Transaminase is a homodimeric cytoplasmic pyridoxal phosphate-dependent enzyme involved in cellular nitrogen metabolism, amino acid metabolism, and liver gluconeogenesis. GPT mediates conversion of major intermediate metabolites, catalyzing reversible transamination between alanine and alpha-ketoglutarate to form pyruvate and glutamate. (NCI)
Glutamic-Pyruvate Transaminase Synonyms
Glutamic-Pyruvate Transaminase, AAT1, ALT1, Alanine Aminotransferase, GPT, GPT1, Glutamic-Alanine Transaminase, Glutamic-Pyruvic Transaminase
Terms in Glutamic-Pyruvate Transaminase category
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