Cancer Terms

Glutathione S-Transferase-M1

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Enzyme -> Transferase -> Alkyltransferase and Aryltransferase -> Glutathione S-Transferase -> Glutathione S-Transferase-M1

Glutathione S-Transferase-M1 Definition

Glutathione S-transferases (GSTs) are a family of phase II enzymes which comprise at least four classes, a, m, p and q. The GSTM1 gene is one of the m-class forms and is classified into three genotypes, GSTM1A, GSTM1B, and GSTM1 (0/0). The GSTM1 (0/0) genotype due to inherited homozygous deletion of both alleles has no enzymatic activity. The GSTM1 (0/0) genotype has been possibly implicated in elevated risks of lung and urothelial cancer. (Japanese Journal of Clinical Oncology,Pages 657-660).

Glutathione S-Transferase-M1 Synonyms

Glutathione S-Transferase M1, GST Class-Mu-1, GSTM1, GSTM1 Protein, GSTM1-1, GSTM1-2, GTH4, Glutathione S-Transferase Mu-1, HB Subunit 4

Terms in Glutathione S-Transferase-M1 category



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