Growth Hormone-Releasing Hormone
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Growth Hormone-Releasing Hormone Definition
This protein belongs to the glucagon family and is a preproprotein that is produced in the hypothalamus. The preproprotein is cleaved to form a 44 aa factor, also called somatocrinin, that acts to stimulate growth hormone release from the pituitary. Variant receptors for somatocrinin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in the gene are a cause of dwarfism, while hypersecretion of the encoded protein is a cause of gigantism. (from RefSeq)
Growth Hormone-Releasing Hormone Synonyms
Growth Hormone Releasing Hormone, GHRH, Growth Hormone-Releasing Hormone, Somatocrinin, Somatoliberin
Terms in Growth Hormone-Releasing Hormone category
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