Cancer Terms

Growth Hormone-Releasing Hormone

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Peptide Hormone -> Hypothalmic Hormone -> Growth Hormone-Releasing Hormone

Growth Hormone-Releasing Hormone Definition

This protein belongs to the glucagon family and is a preproprotein that is produced in the hypothalamus. The preproprotein is cleaved to form a 44 aa factor, also called somatocrinin, that acts to stimulate growth hormone release from the pituitary. Variant receptors for somatocrinin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in the gene are a cause of dwarfism, while hypersecretion of the encoded protein is a cause of gigantism. (from RefSeq)

Growth Hormone-Releasing Hormone Synonyms

Growth Hormone Releasing Hormone, GHRH, Growth Hormone-Releasing Hormone, Somatocrinin, Somatoliberin

Terms in Growth Hormone-Releasing Hormone category



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