Guanine Nucleotide Binding Protein Beta-3

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Signaling Protein -> G Protein -> Heterotrimeric G Protein Subunit -> Guanine Nucleotide Binding Protein Beta-3

Guanine Nucleotide Binding Protein Beta-3 Definition

Encoded by human GNB3 Gene, 340-aa 37-kDa Guanine Nucleotide Binding Protein Beta 3 is a heterotrimeric G protein beta subunit with 7 WD repeats and involved in transmembrane signaling as a transducer that regulates G protein alpha subunits and integrates signals between receptors and effector proteins. The G protein beta and gamma subunits are required for GTPase activity, for GTP replacement of GDP, and for G protein/effector interaction. A splicing polymorphism is associated with essential hypertension and obesity.

Guanine Nucleotide Binding Protein Beta-3 Synonyms

Guanine Nucleotide-Binding Protein G(I)/G(S)/G(T) Subunit Beta-3, G Protein, Beta-3 Subunit, GNB3, GTP-Binding Regulatory Protein Beta-3 Chain, Guanine Nucleotide Binding Protein Beta 3, Guanine Nucleotide-Binding Protein G(I)/G(S)/G(T) Beta Subunit 3, Transducin Beta Chain 3

Terms in Guanine Nucleotide Binding Protein Beta-3 category

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