Guanine Nucleotide Exchange Factor

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Signaling Protein -> Guanine Nucleotide Exchange Factor

Guanine Nucleotide Exchange Factor Definition

GEFs. Proteins that catalyze the release and exchange of GDP for GTP from GTP-binding regulatory proteins, which are active in the GTP-bound form. The prototypical GEF is the eukaryotic initiation factor 2b, eIF-2B. Among other GTP-binding proteins regulated in this manner is p21 ras.

Guanine Nucleotide Exchange Factor Synonyms

Guanine Nucleotide Exchange Factor, GDP Exchange Factors, GDP-GTP Exchange Factors, GEF, Guanine Nucleotide-Exchange Factor, Guanine Nucleotide-Releasing Factor, Guanyl-Nucleotide Exchange Factor, Guanyl-Nucleotide Releasing Factor

Terms in Guanine Nucleotide Exchange Factor category

A Kinase Anchor Protein-13
Guanine Nucleotide-Releasing Factor-2
Link Guanine Nucleotide Exchange Factor-II
MCF2 p66 Protein
RAL Guanine Nucleotide Dissociation Stimulator
Ras Protein Specific Guanine Nucleotide Releasing Factor 1
Ras Protein Specific Guanine Nucleotide Releasing Factor 2
Rho Guanine Nucleotide Exchange Factor-1
Rho Guanine Nucleotide Exchange Factor-5
TIAM1 Protein
Triple Functional Domain Protein
VAV1 Protein
VAV2 Protein
VAV3 Protein