HDAC2 wt Allele

Cancer Terms -> Gene -> Enzyme Gene -> Hydrolase Gene -> HDAC2 Gene -> HDAC2 wt Allele

HDAC2 wt Allele Definition

Human HDAC2 wild-type allele is located within 6q21 and is approximately 30 kb in length. This allele, which encodes histone deacetylase 2 protein, is involved in both the deacetylation of lysine residues on the N-terminal region of the core histones (H2A, H2B, H3 and H4) and the formation of transcriptional repressor complexes. Reduced expression of the HDAC2 gene is associated with chronic obstructive pulmonary disease.

HDAC2 wt Allele Synonyms

HDAC2 wt Allele, Histone Deacetylase 2 wt Allele, RPD3, YAF1

Terms in HDAC2 wt Allele category

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