Cancer Terms

HIF1A wt Allele

Cancer Terms -> Gene -> Protein Complex Subunit Gene -> HIF1A Gene -> HIF1A wt Allele

HIF1A wt Allele Definition

Human HIF1A wild-type allele is located within 14q21-q24 and is approximately 53 kb in length. This allele, which encodes hypoxia-inducible factor 1 alpha protein, is involved in angiogenesis and transcriptional regulation during the cellular adaptive response to hypoxia. Overexpression of the HIF1A gene is associated with several types of cancer such as hepatocellular carcinoma and renal cell carcinoma.

HIF1A wt Allele Synonyms

HIF1A wt Allele, HIF-1alpha, HIF1-Alpha, Hypoxia-Inducible Factor 1, Alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) wt Allele, MOP1

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