HLA-DQ Antigen
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HLA-DQ Antigen Definition
HLA-DQ antigen is a class of glycoproteins that consist of dimers of alpha and beta subunits, which are encoded by the polymorphic human genes HLA-DQA1 and HLA-DQB1, respectively. This protein complex is expressed primarily in lymphoid cells and function to present antigens for CD4+ T lymphocytes. Certain HLA-DQ protein variants are associated with susceptibility to insulin-dependent diabetes mellitus and several autoimmune diseases.
HLA-DQ Antigen Synonyms
HLA-DQ Antigen
Terms in HLA-DQ Antigen category
HLA Class II Histocompatibility Antigen DQ1 Beta Chain
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