HMG Family Gene

Cancer Terms -> Gene -> Regulatory Gene -> HMG Family Gene

HMG Family Gene Definition

Human HMG Family Genes encode ubiquitous non-histone HMG chromatin proteins originally named according to PAGE electrophoretic mobility, shared physical properties, and association with chromatin. Canonical HMG proteins are subdivided into 3 superfamilies with characteristic functional sequence motifs: HMGB (formerly HMG-1/-2), HMGN (formerly HMG-14/-17), and HMGA (formerly HMG-I/Y/C). DNA-binding HMG proteins appear to have roles in matrix stabilization, ssDNA protection, replication, and transcription that influence cell growth, proliferation, differentiation, and death. (NCI)

HMG Family Gene Synonyms

HMG Family Gene

Terms in HMG Family Gene category

HMGA Family Gene
HMGB Family Gene
HMGN Family Gene