HMGA1 wt Allele

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HMGA1 wt Allele Definition

Human HMGA1 wild-type allele is located within 6p21 and is approximately 9 kb in length. This allele, which encodes high mobility group protein HMG-I/HMG-Y, is involved in chromatin remodeling, DNA-dependent transcriptional regulation and inhibition of tumor suppressor p53 protein-dependent apoptosis. The HMGA1 gene is overexpressed in certain types of cancer including breast carcinoma, colorectal cancer, non-small-cell lung carcinoma, epithelial ovarian carcinoma and thyroid cancer.

HMGA1 wt Allele Synonyms

HMGA1 wt Allele, HMG-I(Y) Gene, HMG-R Gene, HMGIY Gene, High Mobility Group AT-Hook 1 wt Allele, High Mobility Group Protein HMG-I/HMG-Y Gene, High Mobility Group Protein HMGI-Y Gene, High Mobility Group Protein Isoforms I and Y Gene, MGC12816 Gene, MGC4242 Gene, MGC4854 Gene, Nonhistone Chromosomal High-Mobility Group Protein HMG-I/HMG-Y Gene

Terms in HMGA1 wt Allele category

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