HMGA2 wt Allele

Cancer Terms -> Gene -> Regulatory Gene -> HMG Family Gene -> HMGA Family Gene -> HMGA2 Gene -> HMGA2 wt Allele

HMGA2 wt Allele Definition

Human HMGA2 wild-type allele is located within 12q15 and is approximately 142 kb in length. This allele, which encodes high mobility group protein HMGI-C, plays a role in chromatin remodeling and DNA-dependent transcriptional regulation. The HMGA2 gene is overexpressed in several types of cancer such as neuroblastomas and pituitary adenomas. Translocation of this gene is associated with lipomas, pulmonary chondroid hamartomas and uterine leiomyomata.

HMGA2 wt Allele Synonyms

HMGA2 wt Allele, BABL, BABL Gene, HMGIC, HMGIC Gene, High Mobility Group AT-Hook 2 wt Allele, High Mobility Group Protein HMGIC Breakpoint Associated with Benign Lipoma Gene, High Mobility Group Protein Isoform I-C Gene, High-Mobility Group (Nonhistone Chromosomal) Protein Isoform I-C Gene, High-Mobility Group Protein HMGI-C Gene, LIPO, LIPO Gene

Terms in HMGA2 wt Allele category

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