HTR2A-T Allele

Cancer Terms -> Gene -> Ligand Binding Protein Gene -> Receptor Gene -> G Protein-Coupled Receptor Gene -> HTR2A Gene -> HTR2A-T Allele

HTR2A-T Allele Definition

HTR2A-T Allele is a variant form of 20-kb 3-exon human HTR2A Gene (GPCR1/5HT2 Family), which encodes Serotonin 5-HT-2A Receptor, a conserved integral membrane 5-HT/serotonin receptor protein involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production by association with G proteins that activate a PI-calcium second messenger system. 5-HT is a biogenic hormone that affects specific receptors as a neurotransmitter, hormone, or mitogen. HTR2A contains several polymorphic sites. Different alleles differ in the concentration of RNA and protein product of 5HTR2A. HTR2A-T Allele contains a single-nucleotide polymorphism (102 C>T) in an intron and is expressed at a higher level than the 102 T>C allele.

HTR2A-T Allele Synonyms

HTR2A 2 Allele, 5-Hydroxytryptamine (Serotonin) Receptor 2A A1 Allele, HTR2A A1, HTR2A A1 Allele, HTR2A T, HTR2A, 102C>T, HTR2A-T, HTR2A-T Allele, HTR2A: g102C>T

HTR2A-T Allele

HTR2A-T Allele Definition

HTR2A-T Allele Synonyms

Terms in HTR2A-T Allele category