Cancer Terms

Hepsulfam

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Antineoplastic Agent -> Alkylating Agent -> Antineoplastic Alkylating Agent -> Alkylsulfonate Compound -> Hepsulfam

Hepsulfam Definition

A bisulfamic ester which is similar in structure to busulfan and belongs to the family of drugs known as alkylsulfonate alkylating agents. Hepsulfam forms covalent linkages with nucleophilic centers in DNA, resulting in depurination, base miscoding, strand scission, DNA-DNA and DNA-protein cross-linking, and cytotoxicity. (NCI04)

Hepsulfam Synonyms

Hepsulfam, 1,7-Heptanediyl Ester Sulfamic Acid, HEPSULFAM, Sulfamic acid, 1,7-heptanediyl ester

Terms in Hepsulfam category



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