Hexokinase-2
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Protein ->
Protein Organized by Function ->
Enzyme ->
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Kinase -> Hexokinase-2
Hexokinase-2 Definition
Expressed in human heart, skeletal muscle, and adipose tissue and encoded by insulin-responsive HK2 Gene (Hexokinase Family), outer mitochondrial membrane-bound 917-amino acid 102-kD monomeric Hexokinase 2 promotes glycolysis. HK2 contains glucose- and ATP-binding sites and a hexokinase domain. The C-terminus contains catalytic activity; membrane binding and regulation associate with the N-terminus. Allosterically regulated by product, HK2 converts aldo-/keto-hexoses to hexose-6-phosphate, the first step of many metabolic pathways. (from LocusLink, Swiss-Prot, OMIM, and NCI)
Hexokinase-2 Synonyms
Hexokinase 2, EC 2.7.1.1, HK II, HK2 Protein, Hexokinase II, Hexokinase, Type II, Hexokinase-2, Muscle, Muscle Form Hexokinase
Terms in Hexokinase-2 category
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