Hippocalcin
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Protein Organized by Function ->
Ligand Binding Protein ->
Calcium Binding Protein -> Hippocalcin
Hippocalcin Definition
Encoded by human HPCA Gene (Recoverin Subfamily), 192-amino acid 22-kD neuron-specific Hippocalcin is myristoylated, plasma membrane-associated, binds two Ca(2+) ions, and contains the EF-hand Ca(2+)-binding motif. Human amino acid sequence shows complete identity (and 92% nucleotide identity) with rat; it is also identical to mouse hippocalcin. Hippocalcin shows striking similarity to photoreceptor Ca(2+)-sensitive proteins that regulate photosignal transduction. Displaying recoverin activity and a Ca(2+)-dependent inhibition of rhodopsin kinase, it may be involved in the Ca(2+)-dependent regulation of rhodopsin phosphorylation. (from LocusLink, Swiss-Prot, OMIM, and NCI)
Hippocalcin Synonyms
Hippocalcin, BDR-2, HPCA, HPCA Protein, Neuron Specific Calcium Binding Protein Hippocalcin, p23K
Terms in Hippocalcin category
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