Histone

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Structural Protein -> Histone

Histone Definition

Major protein component of chromatin. Highly conserved basic proteins, originally classified into classes based on the relative amounts of arginine and lysine in each protein. The various classes are now termed H1, H2A, H2B, H3, and H4. In chromatin, they are found in an octamer, containing two each of H2A, H2B, H3, and H4, complexed with DNA in nucleosomes. The histones in the octamer complex are also known as the core histones. The H1 class of histones, termed the linker histones, is loosely associated with the nucleosome.

Histone Synonyms

Histone

Terms in Histone category

Histone-H1
Histone-H2A
Histone-H2B
Histone-H3
Histone-H4