Histone Deacetylase

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Enzyme -> Hydrolase -> Deacetylase -> Histone Deacetylase

Histone Deacetylase Definition

Histone acetylation and deacetylation alternately exposes and occludes DNA to transcription factors. Histone deacetylation is catalyzed by the histone deacetylases. There are at least 2 classes of HDACs, class I consisting of proteins homologous to yeast Rpd3 (e.g., HDAC1, HDAC2, and HDAC3) and class II consisting of proteins homologous to yeast Hda1 (e.g., HDAC4 and HDAC6). (from OMIM)

Histone Deacetylase Synonyms

Histone Deacetylase, HDAC

Terms in Histone Deacetylase category

Histone Deacetylase-1
Histone Deacetylase-2
Histone Deacetylase-3
Histone Deacetylase-4
Histone Deacetylase-5
Histone Deacetylase-6