Homeobox Protein-A10
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Homeobox Protein-A10 Definition
Encoded by human HOXA10 Gene (ABD-B Family) and expressed spatially/temporally in posterior domains during genitourinary development, 496- and 494-amino acid 41-kD Homeobox Protein A10 isoforms are inhibitory transcription factors, containing a common DNA-binding homeobox domain, that may regulate morphogenesis and differentiation by providing anterior-posterior positional identity. HOXA10 protein is also expressed in adult endometrium during early pregnancy. Bound to 5-prime AA[AT]TTTTATTAC 3-prime DNA, HOXA10 may mediate progesterone regulation of uterine EP3 and EP4. HOXA10 also appears to regulate hematopoietic lineage commitment. (from LocusLink, Swiss-Prot, OMIM, and NCI)
Homeobox Protein-A10 Synonyms
Homeobox Protein Hox-A10, Centaurin Alpha 1-Like, HOX1.8, HOX1H, HOXA10, HOXA10 Protein, Homeobox Protein 1H, Homeobox Protein A10, Homeobox Protein HOXA10, Hox-1H, PL
Terms in Homeobox Protein-A10 category
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