Human Papillomavirus-18
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Human Papillomavirus-18 Definition
A strain of the human papillomavirus virus, (HPV18), has been directly linked to cervical cancer and plays a role in the pathogenesis of the disease. The papillomavirus virus constitutes a protein coat (capsid) surrounding a circular, double-stranded DNA organised into coding and non-coding regions, and induces skin and mucosal epithelial lesions. The virus integrates its DNA at specific chromosomal locations, such as 8q24 and 12q15, which harbours both HPV18 and HPV16. The use of molecular markers such as HPV18 DNA type may allow the identification of patients with early stage cervical cancer at high risk for disease recurrence.
Human Papillomavirus-18 Synonyms
Human Papillomavirus-18, HPV-18
Terms in Human Papillomavirus-18 category
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