Hyaluronan-Mediated Motility Receptor
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Hyaluronan-Mediated Motility Receptor Definition
Encoded by human HMMR Gene and expressed in normal breast tissue, the 724-amino acid 84 kD Hyaluronan-Mediated Motility Receptor is similar to murine Hmmr. A subunit of the HARC complex, the hyaluronan receptor is required for cell motility and may regulate ERK activity. Phosphorylation of several proteins, including pp125-FAK, occurs when Hyaluronan binds HMMR; FAK phosphorylation is necessary for disassembly of focal contacts and motility. HMMR is up regulated in response to wound healing. (from Swiss-Prot, OMIM, and NCI)
Hyaluronan-Mediated Motility Receptor Synonyms
Hyaluronan-Mediated Motility Receptor, CD168 Antigen, HMMR, Intracellular Hyaluronic Acid Binding Protein, Receptor for Hyaluronan-Mediated Motility
Terms in Hyaluronan-Mediated Motility Receptor category
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