Hypoxanthine Phosphoribosyltransferase

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Enzyme -> Transferase -> Glycosyltransferase -> Hypoxanthine Phosphoribosyltransferase

Hypoxanthine Phosphoribosyltransferase Definition

Cytoplasmic Hypoxanthine Phosphoribosyltransferases (Purine/Pyrimidine Phosphoribosyltransferase Family) catalyze the conversion of 5-phosphoribosyl-1-pyrophosphate and hypoxanthine, guanine, or 6-mercaptopurine to the corresponding 5'-mononucleotides and pyrophosphate. The enzyme is important in purine biosynthesis as well as central nervous system functions. (NCI)

Hypoxanthine Phosphoribosyltransferase Synonyms

Hypoxanthine Phosphoribosyltransferase, EC 2.4.2.8, HPRT

Terms in Hypoxanthine Phosphoribosyltransferase category

Hypoxanthine Phosphoribosyltransferase-1